What JWST pipelines and retrieval approaches best handle faint exoplanet spectra?

[Jonathan_M]

I'm a graduate student in astrophysics, and my research involves analyzing transmission spectroscopy data from JWST to characterize exoplanet atmospheres. I'm currently working on a hot Jupiter dataset, and I'm struggling to disentangle the planetary signal from stellar activity and systematic noise in the light curves. For others in the field, what are the most effective data reduction and analysis pipelines you've used for JWST NIRSpec or NIRISS data? How do you approach model selection when fitting atmospheric retrieval models, and what are the current best practices for quantifying uncertainties and avoiding overfitting when the spectral features are so faint?