What are best SDKs and cloud platforms for VQE on near-term hardware?

[Robert.C]

I'm a researcher in computational chemistry, and I'm exploring how near-term quantum computing could be applied to simulate complex molecular interactions that are intractable for classical computers. I've been studying variational quantum algorithms, but I'm struggling to translate theoretical papers into practical implementation on actual quantum hardware or simulators. For others working at this intersection, what are the most promising software development kits and cloud platforms for running these algorithms? How do you approach designing a problem-specific ansatz and managing the significant noise and error rates in current devices to get meaningful results?